Palazzo Dolfin Manin, as it is now called, is a palace in the sestiere of San Marco on the Canal Grande of Venice, northern Italy. It is located near the Palazzo Bembo and Palazzo Dandolo Paolucci, not far from the Rialto Bridge.

The palace was built by the noble Dolfin family starting from 1536, in order to renovate their previous residence, formed by two separate medieval edifices. The construction cost some 30,000 ducats, and was designed by Jacopo Sansovino.