Cancer Drug Target p97
- Color
- Veronica Falconieri Hays
Image of cryo-electron microscopy (cryo-EM) density maps of protein p97 (purple, blue, and green) during inhibition and activation. p97 is a target for cancer drugs in clinical trials, since its inhibition may prevent cancer cells from adequately disposing of excess protein through proteasome degradation. Research on this molecule informed ongoing oncology research and pharmaceutical development.
- Collections: Molecular